IL1B ELISA Kit
Product Sizes
96 wells/kit; with removable strips.
£701.00
OKBB00176-96WELLS
About this Product
- SKU:
- OKBB00176
- Additional Names:
- Catabolin; Hematopoietin 1; IFN beta inducing factor; IL 1; IL 1 beta; IL 1B; IL-1 beta; IL1; IL1 BETA; IL1B; IL1B_HUMAN; IL1F2; Interleukin 1 beta; Interleukin 1 beta precursor; Interleukin-1 beta; LAF; OAF; Osteoclast activating factor; Preinterleukin beta; Pro interleukin 1 beta
- Extra Details:
- Interleukin-1β ( IL-1β) is a potent stimulator of bone resorption whose gene is mapped to 2q14; and has been implicated in the pathogenesis of high bone turnover and osteoporosis. IL-1β; a prominent microglia-derived cytokine; caused oligodendrocyte death in coculture with astrocytes and microglia; but not in pure culture of oligodendrocytes alone1. It also can cause nuclear export of a specific NCOR corepressor complex; resulting in derepression of a specific subset of nuclear factor-kappa-B (NFKB)-regulated genes2. Furthermore; Microenvironmental IL-1β and; to a lesser extent; IL-1α are required for in vivo angiogenesis and invasiveness of different tumor cells3. Additional; the cooperation of IL-1β and PDGFB induces contractile-to-synthetic phenotype modulation of human aortic smooth muscle cells in culture4. Moreover; the association with disease may be explained by the biologic properties of IL-1β; which is an important proinflammatory cytokine and a powerful inhibitor of gastric acid secretion5.
- Gene Details:
- interleukin 1; beta
- Immunogen:
- Expression system for standard: E.coli; Immunogen sequence: A117-S269
- Protein Details:
- Interleukin-1 beta
- Sensitivity:
- <0.15 pg/ml
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 4C for 6 months; at -20C for 12 months. Avoid multiple freeze-thaw cycles (Shipped with wet ice.)
- Supplier:
- Aviva Systems Biology
- Type:
- Assay Kits: ELISAs
