FASL ELISA Kit
Product Sizes
96 wells/kit; with removable strips.
£766.00
OKBB00143-96WELLS
About this Product
- SKU:
- OKBB00143
- Additional Names:
- Apoptosis (APO 1) antigen ligand 1; Apoptosis antigen ligand; APT1LG1; APTL; CD178; CD95 L; CD95 ligand; CD95L; CD95L protein; Fas antigen ligand; FASL; FASLG; TNF superfamily member 6; TNFSF6; Tumor necrosis factor (ligand) superfamily member 6; Tumor necrosis factor ligand superfamily member 6
- Extra Details:
- Fas ligand (FasL or CD95L) is a type-II transmembrane protein that belongs to the tumor necrosis factor (TNF) family. Its binding with its receptor induces apoptosis. The human FASL gene consists of approximately 8 kb and is split into 4 exons. Fas ligand/receptor interactions play an important role in the regulation of the immune system and the progression of cancer. Fas ligand or FasL is a homotrimeric type II transmembrane protein. It signals through trimerization of FasR; which spans the membrane of the "target" cell. This trimerization usually leads to apoptosis; or cell death. Soluble Fas ligand is generated by cleaving membrane-bound FasL at a conserved cleavage site by the external matrix metalloproteinase MMP-7.
- Gene Details:
- Fas ligand
- Immunogen:
- Expression system for standard: CHO; Immunogen sequence: P134-L281
- Protein Details:
- Tumor necrosis factor ligand superfamily member 6
- Sensitivity:
- <2 pg/ml
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 4C for 6 months; at -20C for 12 months. Avoid multiple freeze-thaw cycles (Shipped with wet ice.)
- Supplier:
- Aviva Systems Biology
- Type:
- Assay Kits: ELISAs
