BMP-2 ELISA Kit
Product Sizes
96 wells/kit; with removable strips.
£630.00
OKBB00131-96WELLS
About this Product
- SKU:
- OKBB00131
- Additional Names:
- BDA2; BMP-2; BMP-2A; Bmp2; BMP2_HUMAN; BMP2A; Bone morphogenetic protein 2; Bone morphogenetic protein 2A
- Extra Details:
- Bone morphogenetic protein-2 (BMP-2; BMP 2A) belongs to the transforming growth factor beta (TGF-β) superfamily. It is thought to be involved in cartilage and bone formation during embryogenesis; but may have additional functions in morphogenesis as implied by its expression in various organs and embryonic tissues of mice.1 BMP-2 has been identified as a candidate mediator of retinoid activity. BMP-2 protein induces medulloblastoma cell apoptosis; whereas the BMP-2 antagonist noggin blocks both retinoid and BMP-2-induced apoptosis. BMP-2 also induces p38 mitogen-activated protein kinase (MAPK); which is necessary for BMP-2 and retinoid-induced apoptosis.2 Bone morphogenic proteins (BMPs) are known to promote osteogenesis; and clinical trials are currently underway to evaluate the ability of certain BMPs to promote fracture-healing and spinal fusion.3 The standard product used in this kit is recombinant human BMP-2; constituting dimer by two chains of 114 amino acids with the molecular mass of 26KDa.
- Gene Details:
- bone morphogenetic protein 2
- Immunogen:
- Expression system for standard: CHO; Immunogen sequence: Q283-R396
- Protein Details:
- Bone morphogenetic protein 2
- Sensitivity:
- <2 pg/ml
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 4C for 6 months; at -20C for 12 months. Avoid multiple freeze-thaw cycles (Shipped with wet ice.)
- Supplier:
- Aviva Systems Biology
- Type:
- Assay Kits: ELISAs
