ATM Antibody
Product Sizes
100ul
£392.00
OASG07797-100UL
About this Product
- SKU:
- OASG07797
- Additional Names:
- AT1; ATA; ATC; ATD; ATE; ATDC; TEL1; TELO1
- Clonality:
- Monoclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- The protein encoded by this gene belongs to the PI3/PI4-kinase family. This protein is an important cell cycle checkpoint kinase that phosphorylates; thus; it functions as a regulator of a wide variety of downstream proteins; including tumor suppressor proteins p53 and BRCA1; checkpoint kinase CHK2; checkpoint proteins RAD17 and RAD9; and DNA repair protein NBS1. This protein and the closely related kinase ATR are thought to be master controllers of cell cycle checkpoint signaling pathways that are required for cell response to DNA damage and for genome stability. Mutations in this gene are associated with ataxia telangiectasia; an autosomal recessive disorder.
- Gene Details:
- ATM serine/threonine kinase
- Host:
- Mouse
- Immunogen:
- Recombinant Protein of ATM
- Isotype:
- IgG1
- Protein Details:
- Serine-protein kinase ATM
- Purification:
- The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at -20C. Avoid repeated freeze/thaw cycles.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
