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Antibodies

DDIT3 Antibody

Product Sizes
100ul
£392.00
OASG07776-100UL
About this Product
SKU:
OASG07776
Additional Names:
CHOP; CEBPZ; CHOP10; CHOP-10; GADD153; AltDDIT3; C/EBPzeta
Clonality:
Monoclonal
Concentration:
1 mg/ml
Extra Details:
This gene encodes a member of the CCAAT/enhancer-binding protein (C/EBP) family of transcription factors. The protein functions as a dominant-negative inhibitor by forming heterodimers with other C/EBP members; such as C/EBP and LAP (liver activator protein); and preventing their DNA binding activity. The protein is implicated in adipogenesis and erythropoiesis; is activated by endoplasmic reticulum stress; and promotes apoptosis. Fusion of this gene and FUS on chromosome 16 or EWSR1 on chromosome 22 induced by translocation generates chimeric proteins in myxoid liposarcomas or Ewing sarcoma. Multiple alternatively spliced transcript variants encoding two isoforms with different length have been identified.
Gene Details:
DNA damage inducible transcript 3
Host:
Mouse
Immunogen:
Synthetic Peptide of CHOP
Isotype:
IgG1
Protein Details:
DNA damage-inducible transcript 3 protein
Purification:
The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
Shipping Conditions:
Blue Ice
Storage Conditions:
Store at -20C. Avoid repeated freeze/thaw cycles.
Supplier:
Aviva Systems Biology
Type:
Antibodies: Monoclonal Antibody