TP53 Antibody
Product Sizes
100ul
£359.00
OASG07695-100UL
About this Product
- SKU:
- OASG07695
- Additional Names:
- P53; BCC7; LFS1; BMFS5; TRP53
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- This gene encodes a tumor suppressor protein containing transcriptional activation; DNA binding; and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes; thereby inducing cell cycle arrest; apoptosis; senescence; DNA repair; or changes in metabolism. Mutations in this gene are associated with a variety of human cancers; including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons (PMIDs: 12032546; 20937277).
- Gene Details:
- tumor protein p53
- Host:
- Rabbit
- Immunogen:
- Synthesized peptide derived from human p53 around the methylation site of K370.
- Isotype:
- IgG
- Protein Details:
- Cellular tumor antigen p53
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at -20C. Avoid repeated freeze/thaw cycles.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
