ATP6V1B1 Antibody - C-terminal region
Product Sizes
100ul
£359.00
OASG07496-100UL
About this Product
- SKU:
- OASG07496
- Additional Names:
- VATB; VMA2; VPP3; DRTA2; RTA1B; ATP6B1
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- V-ATPase B1 is a protein encoded by the ATP6V1B1 gene which is approximately 56.8 kDa. V-ATPase B1 is localised to the endomembrane system. It is involved in insulin receptor recycling; innate immune system; metabolism and mTOR signalling pathway. It mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting; zymogen activation; receptor-mediated endocytosis and synaptic vesicle proton gradient generation. V-ATPase B1 is expressed in the cochlea and endolymphatic sac. Mutations in the ATP6V1B1 gene may result in renal tubular acidosis with progressive nerve deafness.
- Gene Details:
- ATPase; H+ transporting; lysosomal 56/58kDa; V1 subunit B1
- Host:
- Rabbit
- Immunogen:
- Synthesized peptide derived from the C-terminal region of human V-ATPase B1. Location: 350-430aa.
- Isotype:
- IgG
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at -20C. Avoid repeated freeze/thaw cycles.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
