TNFSF10 Antibody - middle region
Product Sizes
100ul
£359.00
OASG07286-100UL
About this Product
- SKU:
- OASG07286
- Additional Names:
- TL2; APO2L; CD253; TRAIL; Apo-2L; TNLG6A
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein preferentially induces apoptosis in transformed and tumor cells; but does not appear to kill normal cells although it is expressed at a significant level in most normal tissues. This protein binds to several members of TNF receptor superfamily including TNFRSF10A/TRAILR1; TNFRSF10B/TRAILR2; TNFRSF10C/TRAILR3; TNFRSF10D/TRAILR4; and possibly also to TNFRSF11B/OPG. The activity of this protein may be modulated by binding to the decoy receptors TNFRSF10C/TRAILR3; TNFRSF10D/TRAILR4; and TNFRSF11B/OPG that cannot induce apoptosis. The binding of this protein to its receptors has been shown to trigger the activation of MAPK8/JNK; caspase 8; and caspase 3. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
- Gene Details:
- tumor necrosis factor (ligand) superfamily; member 10
- Host:
- Rabbit
- Immunogen:
- Synthesized peptide derived from the Internal region of human TRAIL. Location: 1-80aa.
- Isotype:
- IgG
- Molecular Weight:
- 30 kDa
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at -20C. Avoid repeated freeze/thaw cycles.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
