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Antibodies

SNCA Antibody

Product Sizes
100ul
£359.00
OASG06961-100UL
About this Product
SKU:
OASG06961
Additional Names:
PD1; NACP; PARK1; PARK4
Clonality:
Polyclonal
Concentration:
1 mg/ml
Extra Details:
Alpha-synuclein is a member of the synuclein family; which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Four alternatively spliced transcripts encoding two different isoforms have been identified for this gene.
Gene Details:
synuclein; alpha (non A4 component of amyloid precursor)
Host:
Rabbit
Immunogen:
Synthesized peptide derived from human Synuclein- Alpha around the phosphorylation site of Y136. Location: 60-140aa.
Isotype:
IgG
Molecular Weight:
20 kDa
Purification:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Shipping Conditions:
Blue Ice
Storage Conditions:
Store at -20C. Avoid repeated freeze/thaw cycles.
Supplier:
Aviva Systems Biology
Type:
Antibodies: Polyclonal Antibody