STAT6 Antibody
Product Sizes
100ul
£359.00
OASG06894-100UL
About this Product
- SKU:
- OASG06894
- Additional Names:
- STAT6B; STAT6C; D12S1644; IL-4-STAT
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors; STAT family members are phosphorylated by the receptor associated kinases; and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X(L); which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2) cells; expression of cell surface markers; and class switch of immunoglobulins. Alternative splicing results in multiple transcript variants.
- Gene Details:
- signal transducer and activator of transcription 6; interleukin-4 induced
- Host:
- Rabbit
- Immunogen:
- Synthesized peptide derived from human Stat6 around the phosphorylation site of Y641. Location: 580-660aa.
- Isotype:
- IgG
- Molecular Weight:
- 94 kDa
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at -20C. Avoid repeated freeze/thaw cycles.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
