APEX1 Antibody
Product Sizes
100ul
£359.00
OASG06313-100UL
About this Product
- SKU:
- OASG06313
- Additional Names:
- APE; APX; APE1; APEN; APEX; HAP1; REF1
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- Apurinic/apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis; by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre-mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site. This gene encodes the major AP endonuclease in human cells. Splice variants have been found for this gene; all encode the same protein.
- Gene Details:
- APEX nuclease (multifunctional DNA repair enzyme) 1
- Host:
- Rabbit
- Immunogen:
- Synthesized peptide derived from the human Ref-1 around the acetylation site of K7.
- Isotype:
- IgG
- Molecular Weight:
- 35 kDa
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at -20C. Avoid repeated freeze/thaw cycles.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
