RB1 Antibody
Product Sizes
100ul
£359.00
OASG06296-100UL
About this Product
- SKU:
- OASG06296
- Additional Names:
- RB; pRb; OSRC; pp110; p105-Rb; PPP1R130; p110-RB1
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active; hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB); bladder cancer; and osteogenic sarcoma.
- Gene Details:
- retinoblastoma 1
- Host:
- Rabbit
- Immunogen:
- Synthesized peptide derived from human Rb around the non-phosphorylation site of S780. Location: 720-800aa.
- Isotype:
- IgG
- Molecular Weight:
- 106 kDa
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at -20C. Avoid repeated freeze/thaw cycles.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
