BRAF Antibody
Product Sizes
100ul
£359.00
OASG06240-100UL
About this Product
- SKU:
- OASG06240
- Additional Names:
- NS7; B-raf; BRAF1; RAFB1; B-RAF1
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- This gene encodes a protein belonging to the raf/mil family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERKs signaling pathway; which affects cell division; differentiation; and secretion. Mutations in this gene are associated with cardiofaciocutaneous syndrome; a disease characterized by heart defects; mental retardation and a distinctive facial appearance. Mutations in this gene have also been associated with various cancers; including non-Hodgkin lymphoma; colorectal cancer; malignant melanoma; thyroid carcinoma; non-small cell lung carcinoma; and adenocarcinoma of lung. A pseudogene; which is located on chromosome X; has been identified for this gene.
- Gene Details:
- B-Raf proto-oncogene; serine/threonine kinase
- Host:
- Rabbit
- Immunogen:
- Synthesized peptide derived from human Raf-B around the phosphorylation site of T599. Location: 540-620aa.
- Isotype:
- IgG
- Molecular Weight:
- 85 kDa
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at -20C. Avoid repeated freeze/thaw cycles.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
