NFKB2 Antibody
Product Sizes
100ul
£359.00
OASG04979-100UL
About this Product
- SKU:
- OASG04979
- Additional Names:
- p52; p100; H2TF1; LYT10; CVID10; LYT-10; NF-kB2; p49/p100
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- This gene encodes a subunit of the transcription factor complex nuclear factor-kappa-B (NFkB). The NFkB complex is expressed in numerous cell types and functions as a central activator of genes involved in inflammation and immune function. The protein encoded by this gene can function as both a transcriptional activator or repressor depending on its dimerization partner. The p100 full-length protein is co-translationally processed into a p52 active form. Chromosomal rearrangements and translocations of this locus have been observed in B cell lymphomas; some of which may result in the formation of fusion proteins. There is a pseudogene for this gene on chromosome 18. Alternative splicing results in multiple transcript variants.
- Gene Details:
- nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
- Host:
- Rabbit
- Immunogen:
- Synthesized peptide derived from human NFKappaB-p100 around the non-phosphorylation site of S865. Location: 810-890aa.
- Isotype:
- IgG
- Molecular Weight:
- 97 kDa
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at -20C. Avoid repeated freeze/thaw cycles.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
