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Antibodies

L1CAM Antibody

Product Sizes
100ul
£359.00
OASG04845-100UL
About this Product
SKU:
OASG04845
Additional Names:
S10; HSAS; MASA; MIC5; SPG1; CAML1; CD171; HSAS1; N-CAML1; NCAM-L1; N-CAM-L1
Clonality:
Polyclonal
Concentration:
1 mg/ml
Extra Details:
The protein encoded by this gene is an axonal glycoprotein belonging to the immunoglobulin supergene family. The ectodomain; consisting of several immunoglobulin-like domains and fibronectin-like repeats (type III); is linked via a single transmembrane sequence to a conserved cytoplasmic domain. This cell adhesion molecule plays an important role in nervous system development; including neuronal migration and differentiation. Mutations in the gene cause X-linked neurological syndromes known as CRASH (corpus callosum hypoplasia; retardation; aphasia; spastic paraplegia and hydrocephalus). Alternative splicing of this gene results in multiple transcript variants; some of which include an alternate exon that is considered to be specific to neurons.
Gene Details:
L1 cell adhesion molecule
Host:
Rabbit
Immunogen:
Synthesized peptide derived from human NCAM-L1 around the phosphorylation site of S1181. Location: 1120-1200aa.
Isotype:
IgG
Molecular Weight:
180 kDa
Purification:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Shipping Conditions:
Blue Ice
Storage Conditions:
Store at -20°C. Avoid repeated freeze/thaw cycles.
Supplier:
Aviva Systems Biology
Type:
Antibodies: Polyclonal Antibody