MADD Antibody - middle region
Product Sizes
100ul
£359.00
OASG04325-100UL
About this Product
- SKU:
- OASG04325
- Additional Names:
- DENN; IG20; DEEAH; NEDDISH; RAB3GEP
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- Tumor necrosis factor alpha (TNF-alpha) is a signaling molecule that interacts with one of two receptors on cells targeted for apoptosis. The apoptotic signal is transduced inside these cells by cytoplasmic adaptor proteins. The protein encoded by this gene is a death domain-containing adaptor protein that interacts with the death domain of TNF-alpha receptor 1 to activate mitogen-activated protein kinase (MAPK) and propagate the apoptotic signal. It is membrane-bound and expressed at a higher level in neoplastic cells than in normal cells. Several transcript variants encoding different isoforms have been described for this gene.
- Gene Details:
- MAP-kinase activating death domain
- Host:
- Rabbit
- Immunogen:
- Synthesized peptide derived from the Internal region of human MADD. Location: 720-800aa.
- Isotype:
- IgG
- Molecular Weight:
- 183 kDa
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at -20C. Avoid repeated freeze/thaw cycles.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
