KCNA3 Antibody
Product Sizes
100ul
£359.00
OASG04149-100UL
About this Product
- SKU:
- OASG04149
- Additional Names:
- MK3; HGK5; HLK3; PCN3; HPCN3; KV1.3; HUKIII
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release; heart rate; insulin secretion; neuronal excitability; epithelial electrolyte transport; smooth muscle contraction; and cell volume. Four sequence-related potassium channel genes - shaker; shaw; shab; and shal - have been identified in Drosophila; and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel; voltage-gated; shaker-related subfamily. This member contains six membrane-spanning domains with a shaker-type repeat in the fourth segment. It belongs to the delayed rectifier class; members of which allow nerve cells to efficiently repolarize following an action potential. It plays an essential role in T-cell proliferation and activation. This gene appears to be intronless and it is clustered together with KCNA2 and KCNA10 genes on chromosome 1.
- Gene Details:
- potassium channel; voltage gated shaker related subfamily A; member 3
- Host:
- Rabbit
- Immunogen:
- Synthesized peptide derived from human Kv1.3 around the phosphorylation site of Y187. Location: 70-150aa.
- Isotype:
- IgG
- Molecular Weight:
- 58 kDa
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at -20C. Avoid repeated freeze/thaw cycles.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
