BAIAP2L1 Antibody - middle region
Product Sizes
100ul
£359.00
OASG03989-100UL
About this Product
- SKU:
- OASG03989
- Additional Names:
- IRTKS
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- This gene encodes a member of the IMD (IRSp53/MIM homology domain) family. Members of this family can be subdivided in two groups; the IRSp53-like and MIM-like; based on the presence or absence of the SH3 (Src homology 3) domain. The protein encoded by this gene contains a conserved IMD; also known as F-actin bundling domain; at the N-terminus; and a canonical SH3 domain near the C-terminus; so it belongs to the IRSp53-like group. This protein is the substrate for insulin receptor tyrosine kinase and binds to the small GTPase Rac. It is involved in signal transduction pathways that link deformation of the plasma membrane and remodeling of the actin cytoskeleton. It also promotes actin assembly and membrane protrusions when overexpressed in mammalian cells; and is essential to the formation of a potent actin assembly complex during EHEC (Enterohemorrhagic Escherichia coli) pedestal formation.
- Gene Details:
- BAI1-associated protein 2-like 1
- Host:
- Rabbit
- Immunogen:
- Synthesized peptide derived from the Internal region of human IRTKS. Location: 80-160aa.
- Isotype:
- IgG
- Molecular Weight:
- 58 kDa
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at -20C. Avoid repeated freeze/thaw cycles.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
