ARHGAP35 Antibody
Product Sizes
100ul
£359.00
OASG03209-100UL
About this Product
- SKU:
- OASG03209
- Additional Names:
- GRF-1; GRLF1; P190A; P190-A; p190RhoGAP; p190ARhoGAP
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- The human glucocorticoid receptor DNA binding factor; which associates with the promoter region of the glucocorticoid receptor gene (hGR gene); is a repressor of glucocorticoid receptor transcription. The amino acid sequence deduced from the cDNA sequences show the presence of three sequence motifs characteristic of a zinc finger and one motif suggestive of a leucine zipper in which 1 cysteine is found instead of all leucines. The GRLF1 enhances the homologous down-regulation of wild-type hGR gene expression. Biochemical analysis suggests that GRLF1 interaction is sequence specific and that transcriptional efficacy of GRLF1 is regulated through its interaction with specific sequence motif. The level of expression is regulated by glucocorticoids.
- Gene Details:
- Rho GTPase activating protein 35
- Host:
- Rabbit
- Immunogen:
- Synthesized peptide derived from human GRF-1 around the phosphorylation site of Y1105. Location: 1040-1120aa.
- Isotype:
- IgG
- Molecular Weight:
- 160 kDa
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at -20C. Avoid repeated freeze/thaw cycles.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
