GRAP Antibody - N-terminal region
Product Sizes
100ul
£359.00
OASG03203-100UL
About this Product
- SKU:
- OASG03203
- Additional Names:
- DFNB114
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- This gene encodes a member of the GRB2/Sem5/Drk family and functions as a cytoplasmic signaling protein which contains an SH2 domain flanked by two SH3 domains. The SH2 domain interacts with ligand-activated receptors for stem cell factor and erythropoietin; and facilitates the formation of a stable complex with the BCR-ABL oncoprotein. This protein also associates with the Ras guanine nucleotide exchange factor SOS1 (son of sevenless homolog 1) through its N-terminal SH3 domain. In general; it couples signals from receptor and cytoplasmic tyrosine kinases to the Ras signaling pathway.
- Gene Details:
- GRB2-related adaptor protein
- Host:
- Rabbit
- Immunogen:
- Synthesized peptide derived from the N-terminal region of human Grap. Location: 10-90aa.
- Isotype:
- IgG
- Molecular Weight:
- 28 kDa
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at -20C. Avoid repeated freeze/thaw cycles.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
