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Antibodies

EPHB2 Antibody - C-terminal region

Product Sizes
100ul
£359.00
OASG02499-100UL
About this Product
SKU:
OASG02499
Additional Names:
DRT; EK5; ERK; CAPB; Hek5; PCBC; EPHT3; Tyro5; BDPLT22
Clonality:
Polyclonal
Concentration:
1 mg/ml
Extra Details:
This gene encodes a member of the Eph receptor family of receptor tyrosine kinase transmembrane glycoproteins. These receptors are composed of an N-terminal glycosylated ligand-binding domain; a transmembrane region and an intracellular kinase domain. They bind ligands called ephrins and are involved in diverse cellular processes including motility; division; and differentiation. A distinguishing characteristic of Eph-ephrin signaling is that both receptors and ligands are competent to transduce a signaling cascade; resulting in bidirectional signaling. This protein belongs to a subgroup of the Eph receptors called EphB. Proteins of this subgroup are distinguished from other members of the family by sequence homology and preferential binding affinity for membrane-bound ephrin-B ligands. Allelic variants are associated with prostate and brain cancer susceptibility. Alternative splicing results in multiple transcript variants.
Gene Details:
EPH receptor B2
Host:
Rabbit
Immunogen:
Synthesized peptide derived from the C-terminal region of human EphB2. Location: 960-1040aa.
Isotype:
IgG
Molecular Weight:
117 kDa
Purification:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Shipping Conditions:
Blue Ice
Storage Conditions:
Store at -20C. Avoid repeated freeze/thaw cycles.
Supplier:
Aviva Systems Biology
Type:
Antibodies: Polyclonal Antibody