TNFRSF25 Antibody - middle region
Product Sizes
100ul
£359.00
OASG02237-100UL
About this Product
- SKU:
- OASG02237
- Additional Names:
- DR3; TR3; DDR3; LARD; APO-3; TRAMP; WSL-1; GEF720; WSL-LR; PLEKHG5; TNFRSF12
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is expressed preferentially in the tissues enriched in lymphocytes; and it may play a role in regulating lymphocyte homeostasis. This receptor has been shown to stimulate NF-kappa B activity and regulate cell apoptosis. The signal transduction of this receptor is mediated by various death domain containing adaptor proteins. Knockout studies in mice suggested the role of this gene in the removal of self-reactive T cells in the thymus. Multiple alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported; most of which are potentially secreted molecules. The alternative splicing of this gene in B and T cells encounters a programmed change upon T-cell activation; which predominantly produces full-length; membrane bound isoforms; and is thought to be involved in controlling lymphocyte proliferation induced by T-cell activation.
- Gene Details:
- tumor necrosis factor receptor superfamily; member 25
- Host:
- Rabbit
- Immunogen:
- Synthesized peptide derived from the Internal region of human DR3. Location: 230-310aa.
- Isotype:
- IgG
- Molecular Weight:
- 45 kDa
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at -20C. Avoid repeated freeze/thaw cycles.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
