DCLK2 Antibody - N-terminal region
Product Sizes
100ul
£359.00
OASG02096-100UL
About this Product
- SKU:
- OASG02096
- Additional Names:
- CL2; DCK2; CLIK2; DCDC3; CLICK2; DCDC3B; DCAMKL2; CLICK-II
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- This gene encodes a member of the protein kinase superfamily and the doublecortin family. The protein encoded by this gene contains two N-terminal doublecortin domains; which bind microtubules and regulate microtubule polymerization; a C-terminal serine/threonine protein kinase domain; which shows substantial homology to Ca2+/calmodulin-dependent protein kinase; and a serine/proline-rich domain in between the doublecortin and the protein kinase domains; which mediates multiple protein-protein interactions. The microtubule-polymerizing activity of the encoded protein is independent of its protein kinase activity. Mouse studies show that the DCX gene; another family member; and this gene share function in the establishment of hippocampal organization and that their absence results in a severe epileptic phenotype and lethality; as described in human patients with lissencephaly. Multiple alternatively spliced transcript variants have been identified.
- Gene Details:
- doublecortin-like kinase 2
- Host:
- Rabbit
- Immunogen:
- Synthesized peptide derived from the N-terminal region of human DCAMKL2. Location: 1-80aa.
- Isotype:
- IgG
- Molecular Weight:
- 83 kDa
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at -20C. Avoid repeated freeze/thaw cycles.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
