CYP1A1 Antibody - middle region
Product Sizes
100ul
£359.00
OASG01965-100UL
About this Product
- SKU:
- OASG01965
- Additional Names:
- AHH; AHRR; CP11; CYP1; CYPIA1; P1-450; P450-C; P450DX
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- This gene; CYP1A1; encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol; steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs); some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown; however; it is able to metabolize some PAHs to carcinogenic intermediates. The gene has been associated with lung cancer risk. A related family member; CYP1A2; is located approximately 25 kb away from CYP1A1 on chromosome 15.
- Gene Details:
- cytochrome P450; family 1; subfamily A; polypeptide 1
- Host:
- Rabbit
- Immunogen:
- Synthesized peptide derived from the Internal region of human CYP1A1/2. Location: 40-120aa.
- Isotype:
- IgG
- Molecular Weight:
- 55 kDa
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at -20C. Avoid repeated freeze/thaw cycles.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
