DDIT3 Antibody
Product Sizes
100ul
£359.00
OASG01560-100UL
About this Product
- SKU:
- OASG01560
- Additional Names:
- CHOP; CEBPZ; CHOP10; CHOP-10; GADD153; AltDDIT3; C/EBPzeta
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- This gene encodes a member of the CCAAT/enhancer-binding protein (C/EBP) family of transcription factors. The protein functions as a dominant-negative inhibitor by forming heterodimers with other C/EBP members; such as C/EBP and LAP (liver activator protein); and preventing their DNA binding activity. The protein is implicated in adipogenesis and erythropoiesis; is activated by endoplasmic reticulum stress; and promotes apoptosis. Fusion of this gene and FUS on chromosome 16 or EWSR1 on chromosome 22 induced by translocation generates chimeric proteins in myxoid liposarcomas or Ewing sarcoma. Multiple alternatively spliced transcript variants encoding two isoforms with different length have been identified.
- Gene Details:
- DNA-damage-inducible transcript 3
- Host:
- Rabbit
- Immunogen:
- Synthesized peptide derived from human CHOP around the phosphorylation site of S30. Location: 10-90aa.
- Isotype:
- IgG
- Molecular Weight:
- 19 kDa
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at -20C. Avoid repeated freeze/thaw cycles.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
