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Antibodies

CDK8 Antibody - N-terminal region

Product Sizes
100ul
£359.00
OASG01457-100UL
About this Product
SKU:
OASG01457
Additional Names:
K35; IDDHBA
Clonality:
Polyclonal
Concentration:
1 mg/ml
Extra Details:
The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28; and Schizosaccharomyces pombe cdc2; and are known to be important regulators of cell cycle progression. This kinase and its regulatory subunit cyclin C are components of the RNA polymerase II holoenzyme complex; which phosphorylates the carboxy-terminal domain (CTD) of the largest subunit of RNA polymerase II. This kinase has also been shown to regulate transcription by targeting the CDK7/cyclin H subunits of the general transcription initiation factor IIH (TFIIH); thus providing a link between the 'Mediator-like' protein complexes and the basal transcription machinery.
Gene Details:
cyclin-dependent kinase 8
Host:
Rabbit
Immunogen:
Synthesized peptide derived from the N-terminal region of human Cdk8. Location: 10-90aa.
Isotype:
IgG
Molecular Weight:
53 kDa
Purification:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Shipping Conditions:
Blue Ice
Storage Conditions:
Store at -20C. Avoid repeated freeze/thaw cycles.
Supplier:
Aviva Systems Biology
Type:
Antibodies: Polyclonal Antibody