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Antibodies

CD177 Antibody - middle region

Product Sizes
100ul
£359.00
OASG01204-100UL
About this Product
SKU:
OASG01204
Additional Names:
NB1; PRV1; HNA2A; PRV-1; HNA-2a; NB1 GP
Clonality:
Polyclonal
Concentration:
1 mg/ml
Extra Details:
This gene encodes a glycosyl-phosphatidylinositol (GPI)-linked cell surface glycoprotein that plays a role in neutrophil activation. The protein can bind platelet endothelial cell adhesion molecule-1 and function in neutrophil transmigration. Mutations in this gene are associated with myeloproliferative diseases. Over-expression of this gene has been found in patients with polycythemia rubra vera. Autoantibodies against the protein may result in pulmonary transfusion reactions; and it may be involved in Wegener's granulomatosis. A related pseudogene; which is adjacent to this gene on chromosome 19; has been identified.
Gene Details:
CD177 molecule
Host:
Rabbit
Immunogen:
Synthesized peptide derived from the Internal region of human CD177.
Isotype:
IgG
Molecular Weight:
46 kDa
Purification:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Shipping Conditions:
Blue Ice
Storage Conditions:
Store at -20C. Avoid repeated freeze/thaw cycles.
Supplier:
Aviva Systems Biology
Type:
Antibodies: Polyclonal Antibody