ALCAM Antibody - C-terminal region
Product Sizes
100ul
£359.00
OASG01199-100UL
About this Product
- SKU:
- OASG01199
- Additional Names:
- MEMD; CD166
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- Cell adhesion molecule that mediates both heterotypic cell-cell contacts via its interaction with CD6; as well as homotypic cell-cell contacts. Promotes T-cell activation and proliferation via its interactions with CD6. Contributes to the formation and maturation of the immunological synapse via its interactions with CD6. Mediates homotypic interactions with cells that express ALCAM. Required for normal hematopoietic stem cell engraftment in the bone marrow. Mediates attachment of dendritic cells onto endothelial cells via homotypic interaction. Inhibits endothelial cell migration and promotes endothelial tube formation via homotypic interactions. Required for normal organization of the lymph vessel network. Required for normal hematopoietic stem cell engraftment in the bone marrow. Plays a role in hematopoiesis.required for normal numbers of hematopoietic stem cells in bone marrow. Promotes in vitro osteoblast proliferation and differentiation. Promotes neurite extension; axon growth and axon guidance.axons grow preferentially on surfaces that contain ALCAM. Mediates outgrowth and pathfinding for retinal ganglion cell axons. [Isoform 3]: Inhibits activities of membrane-bound isoforms by competing for the same interaction partners. Inhibits cell attachment via homotypic interactions. Promotes endothelial cell migration. Inhibits endothelial cell tube formation.
- Gene Details:
- activated leukocyte cell adhesion molecule
- Host:
- Rabbit
- Immunogen:
- Synthesized peptide derived between 481-530 aa from the C-terminal region of human CD166.
- Isotype:
- IgG
- Molecular Weight:
- 65 kDa
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at -20°C. Avoid repeated freeze/thaw cycles.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
