PTPRJ Antibody - middle region
Product Sizes
100ul
£359.00
OASG01181-100UL
About this Product
- SKU:
- OASG01181
- Additional Names:
- DEP1; SCC1; CD148; HPTPeta; R-PTP-ETA
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes; including cell growth; differentiation; mitotic cycle; and oncogenic transformation. This PTP possesses an extracellular region containing five fibronectin type III repeats; a single transmembrane region; and a single intracytoplasmic catalytic domain; and thus represents a receptor-type PTP. This protein is present in all hematopoietic lineages; and was shown to negatively regulate T cell receptor signaling possibly through interfering with the phosphorylation of Phospholipase C Gamma 1 and Linker for Activation of T Cells. This protein can also dephosphorylate the PDGF beta receptor; and may be involved in UV-induced signal transduction. Multiple transcript variants encoding different isoforms have been found for this gene.
- Gene Details:
- protein tyrosine phosphatase; receptor type; J
- Host:
- Rabbit
- Immunogen:
- Synthesized peptide derived from the Internal region of human CD148.
- Isotype:
- IgG
- Molecular Weight:
- 50/150 kDa
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at -20C. Avoid repeated freeze/thaw cycles.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
