IL6ST Antibody
Product Sizes
100ul
£359.00
OASG01174-100UL
About this Product
- SKU:
- OASG01174
- Additional Names:
- CD130; GP130; HIES4; CDW130; IL-6RB; sGP130
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- The protein encoded by this gene is a signal transducer shared by many cytokines; including interleukin 6 (IL6); ciliary neurotrophic factor (CNTF); leukemia inhibitory factor (LIF); and oncostatin M (OSM). This protein functions as a part of the cytokine receptor complex. The activation of this protein is dependent upon the binding of cytokines to their receptors. vIL6; a protein related to IL6 and encoded by the Kaposi sarcoma-associated herpesvirus; can bypass the interleukin 6 receptor (IL6R) and directly activate this protein. Knockout studies in mice suggest that this gene plays a critical role in regulating myocyte apoptosis. Alternatively spliced transcript variants have been described. A related pseudogene has been identified on chromosome 17.
- Gene Details:
- interleukin 6 signal transducer
- Host:
- Rabbit
- Immunogen:
- Synthesized peptide derived from human CD130 around the non-phosphorylation site of S782. Location: 720-800aa.
- Isotype:
- IgG
- Molecular Weight:
- 160 kDa
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at -20C. Avoid repeated freeze/thaw cycles.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
