CAD Antibody
Product Sizes
100ul
£359.00
OASG00925-100UL
About this Product
- SKU:
- OASG00925
- Additional Names:
- CDG1Z; DEE50; GATD4; EIEE50
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- The de novo synthesis of pyrimidine nucleotides is required for mammalian cells to proliferate. This gene encodes a trifunctional protein which is associated with the enzymatic activities of the first 3 enzymes in the 6-step pathway of pyrimidine biosynthesis: carbamoylphosphate synthetase (CPS II); aspartate transcarbamoylase; and dihydroorotase. This protein is regulated by the mitogen-activated protein kinase (MAPK) cascade; which indicates a direct link between activation of the MAPK cascade and de novo biosynthesis of pyrimidine nucleotides. Alternative splicing results in multiple transcript variants encoding different isoforms.
- Gene Details:
- carbamoyl-phosphate synthetase 2; aspartate transcarbamylase; and dihydroorotase
- Host:
- Rabbit
- Immunogen:
- Synthesized peptide derived from human CAD around the phosphorylation site of T456. Location: 400-480aa.
- Isotype:
- IgG
- Molecular Weight:
- 250 kDa
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at -20C. Avoid repeated freeze/thaw cycles.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
