BLNK Antibody
Product Sizes
100ul
£359.00
OASG00778-100UL
About this Product
- SKU:
- OASG00778
- Additional Names:
- bca; AGM4; BASH; LY57; SLP65; BLNK-S; SLP-65
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- This gene encodes a cytoplasmic linker or adaptor protein that plays a critical role in B cell development. This protein bridges B cell receptor-associated kinase activation with downstream signaling pathways; thereby affecting various biological functions. The phosphorylation of five tyrosine residues is necessary for this protein to nucleate distinct signaling effectors following B cell receptor activation. Mutations in this gene cause hypoglobulinemia and absent B cells; a disease in which the pro- to pre-B-cell transition is developmentally blocked. Deficiency in this protein has also been shown in some cases of pre-B acute lymphoblastic leukemia. Alternatively spliced transcript variants have been found for this gene.
- Gene Details:
- B-cell linker
- Host:
- Rabbit
- Immunogen:
- Synthesized peptide derived from human BLNK around the phosphorylation site of Y84. Location: 20-100aa.
- Isotype:
- IgG
- Molecular Weight:
- 65 kDa
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at -20C. Avoid repeated freeze/thaw cycles.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
