BCL2L11 Antibody
Product Sizes
100ul
£359.00
OASG00769-100UL
About this Product
- SKU:
- OASG00769
- Additional Names:
- BAM; BIM; BOD
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The protein encoded by this gene contains a Bcl-2 homology domain 3 (BH3). It has been shown to interact with other members of the BCL-2 protein family and to act as an apoptotic activator. The expression of this gene can be induced by nerve growth factor (NGF); as well as by the forkhead transcription factor FKHR-L1; which suggests a role of this gene in neuronal and lymphocyte apoptosis. Transgenic studies of the mouse counterpart suggested that this gene functions as an essential initiator of apoptosis in thymocyte-negative selection. Several alternatively spliced transcript variants of this gene have been identified.
- Gene Details:
- BCL2-like 11 (apoptosis facilitator)
- Host:
- Rabbit
- Immunogen:
- Synthesized peptide derived from human Bim around the phosphorylation site of S59. Location: 1-80aa.
- Isotype:
- IgG
- Molecular Weight:
- 25/22 kDa
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at -20C. Avoid repeated freeze/thaw cycles.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
