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Antibodies

BAD Antibody

Product Sizes
100ul
£359.00
OASG00677-100UL
About this Product
SKU:
OASG00677
Additional Names:
BBC2; BCL2L8
Clonality:
Polyclonal
Concentration:
1 mg/ml
Extra Details:
The protein encoded by this gene is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-2; and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase; as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein. Alternative splicing of this gene results in two transcript variants which encode the same isoform.
Gene Details:
BCL2-associated agonist of cell death
Host:
Rabbit
Immunogen:
Synthesized peptide derived from human Bad around the phosphorylation site of S134. Location: 70-150aa.
Isotype:
IgG
Molecular Weight:
28 kDa
Purification:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Shipping Conditions:
Blue Ice
Storage Conditions:
Store at -20C. Avoid repeated freeze/thaw cycles.
Supplier:
Aviva Systems Biology
Type:
Antibodies: Polyclonal Antibody