ATR Antibody
Product Sizes
100ul
£359.00
OASG00649-100UL
About this Product
- SKU:
- OASG00649
- Additional Names:
- FRP1; MEC1; SCKL; FCTCS; SCKL1
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- The protein encoded by this gene belongs the PI3/PI4-kinase family; and is most closely related to ATM; a protein kinase encoded by the gene mutated in ataxia telangiectasia. This protein and ATM share similarity with Schizosaccharomyces pombe rad3; a cell cycle checkpoint gene required for cell cycle arrest and DNA damage repair in response to DNA damage. This kinase has been shown to phosphorylate checkpoint kinase CHK1; checkpoint proteins RAD17; and RAD9; as well as tumor suppressor protein BRCA1. Mutations of this gene are associated with Seckel syndrome. An alternatively spliced transcript variant of this gene has been reported; however; its full length nature is not known. Transcript variants utilizing alternative polyA sites exist.
- Gene Details:
- ATR serine/threonine kinase
- Host:
- Rabbit
- Immunogen:
- Synthesized peptide derived from human ATR around the phosphorylation site of S428. Location: 370-450aa.
- Isotype:
- IgG
- Molecular Weight:
- 300 kDa
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at -20C. Avoid repeated freeze/thaw cycles.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
