ATF1 Antibody
Product Sizes
100ul
£359.00
OASG00601-100UL
About this Product
- SKU:
- OASG00601
- Additional Names:
- TREB36; EWS-ATF1; FUS/ATF-1
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- This gene encodes an activating transcription factor; which belongs to the ATF subfamily and bZIP (basic-region leucine zipper) family. It influences cellular physiologic processes by regulating the expression of downstream target genes; which are related to growth; survival; and other cellular activities. This protein is phosphorylated at serine 63 in its kinase-inducible domain by serine/threonine kinases; cAMP-dependent protein kinase A; calmodulin-dependent protein kinase I/II; mitogen- and stress-activated protein kinase and cyclin-dependent kinase 3 (cdk-3). Its phosphorylation enhances its transactivation and transcriptional activities; and enhances cell transformation. Fusion of this gene and FUS on chromosome 16 or EWSR1 on chromosome 22 induced by translocation generates chimeric proteins in angiomatoid fibrous histiocytoma and clear cell sarcoma. This gene has a pseudogene on chromosome 6.
- Gene Details:
- activating transcription factor 1
- Host:
- Rabbit
- Immunogen:
- Synthesized peptide derived from human ATF-1 around the non-phosphorylation site of S63. Location: 1-80aa.
- Isotype:
- IgG
- Molecular Weight:
- 29 kDa
- Purification:
- Affinity purified from rabbit anti-serum by affinity chromatography
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at -20°C for 1 year. Avoid repeated freeze/thaw cycles.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
