ARRB1 Antibody
Product Sizes
100ul
£359.00
OASG00565-100UL
About this Product
- SKU:
- OASG00565
- Additional Names:
- ARB1; ARR1
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones; neurotransmitters; or sensory signals. Arrestin beta 1 is a cytosolic protein and acts as a cofactor in the beta-adrenergic receptor kinase (BARK) mediated desensitization of beta-adrenergic receptors. Besides the central nervous system; it is expressed at high levels in peripheral blood leukocytes; and thus the BARK/beta-arrestin system is believed to play a major role in regulating receptor-mediated immune functions. Alternatively spliced transcripts encoding different isoforms of arrestin beta 1 have been described.
- Gene Details:
- arrestin; beta 1
- Host:
- Rabbit
- Immunogen:
- Synthesized peptide derived from human Arrestin-Beta-1 around the phosphorylation site of S412. Location: 350-430aa.
- Isotype:
- IgG
- Molecular Weight:
- 47 kDa
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at -20C. Avoid repeated freeze/thaw cycles.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
