Skip to content

Basket

You currently have no items in your basket.

Total (excl. vat) £0.00
View basket & checkout
Antibodies

ADRA1B Antibody - C-terminal region

Product Sizes
100ul
£359.00
OASG00519-100UL
About this Product
SKU:
OASG00519
Additional Names:
ADRA1; ALPHA1BAR
Clonality:
Polyclonal
Concentration:
1 mg/ml
Extra Details:
Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells. There are 3 alpha-1-AR subtypes: alpha-1A; -1B and -1D; all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. This gene encodes alpha-1B-adrenergic receptor; which induces neoplastic transformation when transfected into NIH 3T3 fibroblasts and other cell lines. Thus; this normal cellular gene is identified as a protooncogene. This gene comprises 2 exons and a single large intron of at least 20 kb that interrupts the coding region.
Gene Details:
adrenoceptor alpha 1B
Host:
Rabbit
Immunogen:
Synthesized peptide derived from the C-terminal region of human AR- Alpha1B. Location: 410-490aa.
Isotype:
IgG
Molecular Weight:
60 kDa
Purification:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Shipping Conditions:
Blue Ice
Storage Conditions:
Store at -20C. Avoid repeated freeze/thaw cycles.
Supplier:
Aviva Systems Biology
Type:
Antibodies: Polyclonal Antibody