APLN Antibody - C-terminal region
Product Sizes
100ul
£359.00
OASG00449-100UL
About this Product
- SKU:
- OASG00449
- Additional Names:
- APEL; XNPEP2
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- Endogenous ligand for the apelin receptor (APLNR). Drives internalization of the apelin receptor. Apelin-36 dissociates more hardly than (pyroglu)apelin-13 from APLNR. Hormone involved in the regulation of cardiac precursor cell movements during gastrulation and heart morphogenesis. Has an inhibitory effect on cytokine production in response to T-cell receptor/CD3 cross-linking.the oral intake of apelin in the colostrum and the milk might therefore modulate immune responses in neonates. Plays a role in early coronary blood vessels formation. Mediates myocardial contractility in an ERK1/2-dependent manner. May also have a role in the central control of body fluid homeostasis by influencing vasopressin release and drinking behavior. (Microbial infection) Endogenous ligand for the apelin receptor (APLNR); an alternative coreceptor with CD4 for HIV-1 infection. Inhibits HIV-1 entry in cells coexpressing CD4 and APLNR. Apelin-36 has a greater inhibitory activity on HIV infection than other synthetic apelin derivatives.
- Gene Details:
- apelin
- Host:
- Rabbit
- Immunogen:
- Synthesized peptide derived between 23-72 amino acids from the C-terminal region of human Apelin.
- Isotype:
- IgG
- Purification:
- The antibody was affinity purified from rabbit anti-serum by affinity chromatography.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at -20°C. Avoid repeated freeze/thaw cycles.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
