APAF1 Antibody - C-terminal region
Product Sizes
100ul
£359.00
OASG00438-100UL
About this Product
- SKU:
- OASG00438
- Additional Names:
- CED4; APAF-1
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- This gene encodes a cytoplasmic protein that initiates apoptosis. This protein contains several copies of the WD-40 domain; a caspase recruitment domain (CARD); and an ATPase domain (NB-ARC). Upon binding cytochrome c and dATP; this protein forms an oligomeric apoptosome. The apoptosome binds and cleaves caspase 9 preproprotein; releasing its mature; activated form. Activated caspase 9 stimulates the subsequent caspase cascade that commits the cell to apoptosis. Alternative splicing results in several transcript variants encoding different isoforms.
- Gene Details:
- apoptotic peptidase activating factor 1
- Host:
- Rabbit
- Immunogen:
- Synthesized peptide derived from the C-terminal region of human Apaf-1-ALT. Location: 260-340aa.
- Isotype:
- IgG
- Molecular Weight:
- 40 kDa
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at -20C. Avoid repeated freeze/thaw cycles.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
