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Antibodies

ALDOB Antibody - middle region

Product Sizes
100ul
£359.00
OASG00313-100UL
About this Product
SKU:
OASG00313
Additional Names:
ALDB; ALDO2
Clonality:
Polyclonal
Concentration:
1 mg/ml
Extra Details:
Fructose-1;6-bisphosphate aldolase (EC 4.1.2.13) is a tetrameric glycolytic enzyme that catalyzes the reversible conversion of fructose-1;6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Vertebrates have 3 aldolase isozymes which are distinguished by their electrophoretic and catalytic properties. Differences indicate that aldolases A; B; and C are distinct proteins; the products of a family of related 'housekeeping' genes exhibiting developmentally regulated expression of the different isozymes. The developing embryo produces aldolase A; which is produced in even greater amounts in adult muscle where it can be as much as 5% of total cellular protein. In adult liver; kidney and intestine; aldolase A expression is repressed and aldolase B is produced. In brain and other nervous tissue; aldolase A and C are expressed about equally. There is a high degree of homology between aldolase A and C. Defects in ALDOB cause hereditary fructose intolerance.
Gene Details:
aldolase B; fructose-bisphosphate
Host:
Rabbit
Immunogen:
Synthesized peptide derived from the Internal region of human Aldolase B. Location: 80-160aa.
Isotype:
IgG
Molecular Weight:
39 kDa
Purification:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Shipping Conditions:
Blue Ice
Storage Conditions:
Store at -20C. Avoid repeated freeze/thaw cycles.
Supplier:
Aviva Systems Biology
Type:
Antibodies: Polyclonal Antibody