AIRE Antibody - middle region
Product Sizes
100ul
£359.00
OASG00252-100UL
About this Product
- SKU:
- OASG00252
- Additional Names:
- APS1; APSI; PGA1; AIRE1; APECED
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- This gene encodes a transcriptional regulator that forms nuclear bodies and interacts with the transcriptional coactivator CREB binding protein. The encoded protein plays an important role in immunity by regulating the expression of autoantigens and negative selection of autoreactive T-cells in the thymus. Mutations in this gene cause the rare autosomal-recessive systemic autoimmune disease termed autoimmune polyendocrinopathy with candidiasis and ectodermal dystrophy (APECED).
- Gene Details:
- autoimmune regulator
- Host:
- Rabbit
- Immunogen:
- Synthesized peptide derived from the Internal region of human AIRE-1. Location: 60-140aa.
- Isotype:
- IgG
- Molecular Weight:
- 60 kDa
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at -20C. Avoid repeated freeze/thaw cycles.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
