ACHE Antibody - middle region
Product Sizes
100ul
£359.00
OASG00154-100UL
About this Product
- SKU:
- OASG00154
- Additional Names:
- YT; ACEE; ARACHE; N-ACHE
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- Acetylcholinesterase hydrolyzes the neurotransmitter; acetylcholine at neuromuscular junctions and brain cholinergic synapses; and thus terminates signal transmission. It is also found on the red blood cell membranes; where it constitutes the Yt blood group antigen. Acetylcholinesterase exists in multiple molecular forms which possess similar catalytic properties; but differ in their oligomeric assembly and mode of cell attachment to the cell surface. It is encoded by the single ACHE gene; and the structural diversity in the gene products arises from alternative mRNA splicing; and post-translational associations of catalytic and structural subunits. The major form of acetylcholinesterase found in brain; muscle and other tissues is the hydrophilic species; which forms disulfide-linked oligomers with collagenous; or lipid-containing structural subunits. The other; alternatively spliced form; expressed primarily in the erythroid tissues; differs at the C-terminal end; and contains a cleavable hydrophobic peptide with a GPI-anchor site. It associates with the membranes through the phosphoinositide (PI) moieties added post-translationally.
- Gene Details:
- acetylcholinesterase (Yt blood group)
- Host:
- Rabbit
- Immunogen:
- Synthesized peptide derived from the Internal region of human AChE.
- Isotype:
- IgG
- Molecular Weight:
- 70 kDa
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at -20C. Avoid repeated freeze/thaw cycles.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
