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Antibodies

ARNTL Antibody

Product Sizes
100ul
£359.00
OASG00149-100UL
About this Product
SKU:
OASG00149
Additional Names:
TIC; JAP3; MOP3; BMAL1; PASD3; BMAL1c; bHLHe5
Clonality:
Polyclonal
Concentration:
1 mg/ml
Extra Details:
The protein encoded by this gene is a basic helix-loop-helix protein that forms a heterodimer with CLOCK. This heterodimer binds E-box enhancer elements upstream of Period (PER1; PER2; PER3) and Cryptochrome (CRY1; CRY2) genes and activates transcription of these genes. PER and CRY proteins heterodimerize and repress their own transcription by interacting in a feedback loop with CLOCK/ARNTL complexes. Defects in this gene have been linked to infertility; problems with gluconeogenesis and lipogenesis; and altered sleep patterns. Several transcript variants encoding different isoforms have been found for this gene.
Gene Details:
aryl hydrocarbon receptor nuclear translocator-like
Host:
Rabbit
Immunogen:
Synthesized peptide derived from human BMAL1 around the acetylation site of K538.
Isotype:
IgG
Molecular Weight:
69 kDa
Purification:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Shipping Conditions:
Blue Ice
Storage Conditions:
Store at -20C. Avoid repeated freeze/thaw cycles.
Supplier:
Aviva Systems Biology
Type:
Antibodies: Polyclonal Antibody