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Antibodies

ABCB7 Antibody - C-terminal region

Product Sizes
100ul
£359.00
OASG00101-100UL
About this Product
SKU:
OASG00101
Additional Names:
ABC7; ASAT; Atm1p; EST140535
Clonality:
Polyclonal
Concentration:
1 mg/ml
Extra Details:
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1; MDR/TAP; MRP; ALD; OABP; GCN20; White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This gene encodes a half-transporter involved in the transport of heme from the mitochondria to the cytosol. With iron/sulfur cluster precursors as its substrates; this protein may play a role in metal homeostasis. Mutations in this gene have been associated with mitochondrial iron accumulation and isodicentric (X)(q13) and sideroblastic anemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Gene Details:
ATP-binding cassette; sub-family B (MDR/TAP); member 7
Host:
Rabbit
Immunogen:
Synthesized peptide derived from the C-terminal region of human ABCB7. Location: 660-740aa.
Isotype:
IgG
Molecular Weight:
83 kDa
Purification:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Shipping Conditions:
Blue Ice
Storage Conditions:
Store at -20C. Avoid repeated freeze/thaw cycles.
Supplier:
Aviva Systems Biology
Type:
Antibodies: Polyclonal Antibody