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Antibodies

VGLUT1 Antibody

Product Sizes
100ug
£593.00
OASE00242-100UG
About this Product
SKU:
OASE00242
Additional Names:
BNPI; SLC17A1; SLC17A1/VGLUT1; Solute Carrier family 17 member 7; Vesicular glutamate transporter 1; VGLUT 1; Brain-specific Na(+)-dependent inorganic phosphate cotransporter
translate.label.attr.clone:
S28-9
Clonality:
Monoclonal
Conjugate:
Unconjugated
Concentration:
1 mg/ml
Extra Details:
VGLUT1 is expressed in a subset of glutamate neurons and transports glutamate into native synaptic vesicles from the brain; exhibiting a conductance for chloride that is blocked by glutamate (1). Vesicular glutamate transport has a substantially lower apparent affinity than the plasma membrane excitatory amino acid transporters. Glutamate transport by VGLUT1 is saturated with a K(m) of approximately 2 mM; in the same range as transport by synaptic vesicles. Finally; plasma membrane glutamate transporters recognize both aspartate and glutamate as substrates; whereas VGLUT1 does not recognize aspartate (2).
Gene Details:
solute carrier family 17 (vesicular glutamate transporter); member 7
Host:
Mouse
Immunogen:
Fusion protein amino acids 493-560 (cytoplasmic C-terminus) of rat VGlut1
Isotype:
IgG1
Purification:
Protein G Purified
Shipping Conditions:
Blue Ice
Storage Conditions:
Store at -20°C for 1 year. Avoid repeated freeze/thaw cycles.
Supplier:
Aviva Systems Biology
Type:
Antibodies: Monoclonal Antibody