Human TRAIL Antibody
Product Sizes
0.5 mg
£532.00
OASB01318-0.5MG
About this Product
- SKU:
- OASB01318
- Additional Names:
- TL2; APO2L; CD253; TRAIL; Apo-2L; TNLG6A
- translate.label.attr.clone:
- SB91c
- Clonality:
- Monoclonal
- Conjugate:
- Unconjugated
- Concentration:
- 0.5 mg/mL
- Extra Details:
- The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein preferentially induces apoptosis in transformed and tumor cells; but does not appear to kill normal cells although it is expressed at a significant level in most normal tissues. This protein binds to several members of TNF receptor superfamily including TNFRSF10A/TRAILR1; TNFRSF10B/TRAILR2; TNFRSF10C/TRAILR3; TNFRSF10D/TRAILR4; and possibly also to TNFRSF11B/OPG. The activity of this protein may be modulated by binding to the decoy receptors TNFRSF10C/TRAILR3; TNFRSF10D/TRAILR4; and TNFRSF11B/OPG that cannot induce apoptosis. The binding of this protein to its receptors has been shown to trigger the activation of MAPK8/JNK; caspase 8; and caspase 3. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
- Gene Details:
- Tumor necrosis factor ligand superfamily member 10
- Host:
- Mouse
- Immunogen:
- Recombinant TRAIL
- Isotype:
- IgG2b
- Protein Details:
- tumor necrosis factor ligand superfamily member 10
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 2-8C
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
