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Antibodies

Human TLR4 Antibody

Product Sizes
0.1 mg
£370.00
OASB01314-0.1MG
About this Product
SKU:
OASB01314
Additional Names:
TOLL; CD284; TLR-4; ARMD10
Clonality:
Monoclonal
Conjugate:
Unconjugated
Concentration:
0.5 mg/mL
Extra Details:
The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns that are expressed on infectious agents; and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor has been implicated in signal transduction events induced by lipopolysaccharide (LPS) found in most gram-negative bacteria. Mutations in this gene have been associated with differences in LPS responsiveness. Multiple transcript variants encoding different isoforms have been found for this gene.
Gene Details:
Toll-like receptor 4
Host:
Mouse
Isotype:
IgG2a
Protein Details:
toll-like receptor 4
Shipping Conditions:
Blue Ice
Storage Conditions:
Store at 2-8C
Supplier:
Aviva Systems Biology
Type:
Antibodies: Monoclonal Antibody