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Antibodies

Human TLR2 Antibody : LE/AF

Product Sizes
0.1 mg
£528.00
OASB01313-0.1MG
About this Product
SKU:
OASB01313
Additional Names:
TIL4; CD282
translate.label.attr.clone:
2B4A1
Clonality:
Monoclonal
Conjugate:
LE: Low Endotoxin; AF: Azide Free
Concentration:
0.5 mg/mL
Extra Details:
The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. This protein is a cell-surface protein that can form heterodimers with other TLR family members to recognize conserved molecules derived from microorganisms known as pathogen-associated molecular patterns (PAMPs). Activation of TLRs by PAMPs leads to an up-regulation of signaling pathways to modulate the host's inflammatory response. This gene is also thought to promote apoptosis in response to bacterial lipoproteins. This gene has been implicated in the pathogenesis of several autoimmune diseases. Alternative splicing results in multiple transcript variants.
Gene Details:
Toll-like receptor 2
Host:
Mouse
Immunogen:
Recombinant TLR2
Isotype:
IgG2a
Protein Details:
toll-like receptor 2
Shipping Conditions:
Dry Ice
Storage Conditions:
Store at -20C
Supplier:
Aviva Systems Biology
Type:
Antibodies: Monoclonal Antibody