Human TLR2 Antibody : APC
Product Sizes
100 tests
£658.00
OASB01312-100TESTS
About this Product
- SKU:
- OASB01312
- Additional Names:
- TIL4; CD282
- translate.label.attr.clone:
- 2B4A1
- Clonality:
- Monoclonal
- Conjugate:
- APC
- Concentration:
- Lot specific
- Extra Details:
- The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. This protein is a cell-surface protein that can form heterodimers with other TLR family members to recognize conserved molecules derived from microorganisms known as pathogen-associated molecular patterns (PAMPs). Activation of TLRs by PAMPs leads to an up-regulation of signaling pathways to modulate the host's inflammatory response. This gene is also thought to promote apoptosis in response to bacterial lipoproteins. This gene has been implicated in the pathogenesis of several autoimmune diseases. Alternative splicing results in multiple transcript variants.
- Gene Details:
- Toll-like receptor 2
- Host:
- Mouse
- Immunogen:
- Recombinant TLR2
- Isotype:
- IgG2a
- Protein Details:
- toll-like receptor 2
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 2-8C
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
